The LUCA
Platform


A proprietary platform for discovery and development of live biotherapeutics to protect against vaginal dysbiosis and restore homeostatic function to the vaginal microbiome.




SOURCING

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Vaginal microbiota library of 1,000+ strains and gene catalogue assembled over 15 years from the research group of Dr. Jacques Ravel and funded by the National Institute of Health and the Bill and Melinda Gates Foundation.


ISOLATION

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Individual bacteria strains on selective media.


IDENTIFICATION

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Comprehensive human vaginal non-redundant gene catalogue annotated from 17 diverse protein databases and based on over 1,500 vaginal metagenomes.


SCREENING

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Analysis of core genome to identify genes associated with novel protective features that maintain stability of vaginal communities over time.


MECHANISM OF ACTION

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Microbiology | In vivo metabolite production | Transcriptomics  |  Immunology


DEVELOPMENT

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Scale Up | Lyophilization | Stability | Potency